Mikrosatellite Instability (MSI)
Mikrosatelit hotels (short tandem repeats), 2 – 10 nukleotidlik are a recurrent motif that consists of repetitive DNA sequences. Mismatch repair (MMR) genes ( MLH1, PMS2, MSH2, MSH6 ) that defects in DNA synthesis , and mutations in this region are not repaired during mikrosatelit mikrosatelit instability (MSI) causes.
